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Sequence-structure-function characterization of the emerging tetracycline destructase family of antibiotic resistance enzymes - Communications Biology
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Tetracycline destructases (TDases) are flavin monooxygenases which can confer resistance to all generations of tetracycline antibiotics. The recent increase in the number and diversity of reported TDase sequences enables a deep investigation of the TDase sequence-structure-function landscape.
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