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12 days ago

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Cell shape sensing licenses dendritic cells for homeostatic migration to lymph nodes - Nature Immunology

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Cell shape sensing licenses dendritic cells for homeostatic migration to lymph nodes - Nature Immunology

Immune cells experience large cell shape changes during environmental patrolling because of the physical constraints that they encounter while migrating through tissues. These cells can adapt to such deformation events using dedicated shape-sensing pathways. However, how shape sensing affects immune cell function is mostly unknown.

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Cell shape sensing licenses dendritic cells for homeostatic migration to lymph nodes - Nature Immunology

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Cell shape sensing licenses dendritic cells for homeostatic migration to lymph nodes - Nature Immunology

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