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Digital colloid-enhanced Raman spectroscopy by single-molecule counting - Nature
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Quantitative detection of various molecules at very low concentrations in complex mixtures has been the main objective in many fields of science and engineering, from the detection of cancer-causing mutagens and early disease markers to environmental pollutants and bioterror agents1–5. Moreover, technologies that can detect these analytes without external labels or modifications are extremely valuable and often preferred6.
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