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Assessing the laboratory performance of AI-generated enzymes - Nature Biotechnology

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Assessing the laboratory performance of AI-generated enzymes - Nature Biotechnology

A set of 20 computational metrics was evaluated to determine whether they could predict the functionality of synthetic enzyme sequences produced by generative protein models, resulting in the development of a computational filter, COMPSS, that increased experimental success rates by 50–150%, tested in over 500 natural and AI-generated enzymes.

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Assessing the laboratory performance of AI-generated enzymes - Nature Biotechnology

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Assessing the laboratory performance of AI-generated enzymes - Nature Biotechnology

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