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18 days ago

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Single-mitosis dissection of acute and chronic DNA mutagenesis and repair - Nature Genetics

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Single-mitosis dissection of acute and chronic DNA mutagenesis and repair - Nature Genetics

How chronic mutational processes and punctuated bursts of DNA damage drive evolution of the cancer genome is poorly understood. Here, we demonstrate a strategy to disentangle and quantify distinct mechanisms underlying genome evolution in single cells, during single mitoses and at single-strand resolution.

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Single-mitosis dissection of acute and chronic DNA mutagenesis and repair - Nature Genetics

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Single-mitosis dissection of acute and chronic DNA mutagenesis and repair - Nature Genetics

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