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Improving prime editing with an endogenous small RNA-binding protein - Nature

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Improving prime editing with an endogenous small RNA-binding protein - Nature

Prime editing enables the precise modification of genomes through reverse transcription of template sequences appended to the 3′ ends of CRISPR–Cas guide RNAs1. To identify cellular determinants of prime editing, we developed scalable prime editing reporters and performed genome-scale CRISPR-interference screens.

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Improving prime editing with an endogenous small RNA-binding protein - Nature

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Improving prime editing with an endogenous small RNA-binding protein - Nature

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