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Targeting and engineering long non-coding RNAs for cancer therapy - Nature Reviews Genetics

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Targeting and engineering long non-coding RNAs for cancer therapy - Nature Reviews Genetics

RNA therapeutics (RNATx) aim to treat diseases, including cancer, by targeting or employing RNA molecules for therapeutic purposes. Amongst the most promising targets are long non-coding RNAs (lncRNAs), which regulate oncogenic molecular networks in a cell type-restricted manner. lncRNAs are distinct from protein-coding genes in important ways that increase their therapeutic potential yet also present hurdles to conventional clinical development.

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Targeting and engineering long non-coding RNAs for cancer therapy - Nature Reviews Genetics

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Targeting and engineering long non-coding RNAs for cancer therapy - Nature Reviews Genetics

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