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Enhanced branched-chain amino acid metabolism improves age-related reproduction in C. elegans - Nature Metabolism

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Enhanced branched-chain amino acid metabolism improves age-related reproduction in C. elegans - Nature Metabolism

Reproductive ageing is one of the earliest human ageing phenotypes, and mitochondrial dysfunction has been linked to oocyte quality decline; however, it is not known which mitochondrial metabolic processes are critical for oocyte quality maintenance with age. To understand how mitochondrial processes contribute to Caenorhabditis elegans oocyte quality, we characterized the mitochondrial proteomes of young and aged wild-type and long-reproductive daf-2 mutants.

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Enhanced branched-chain amino acid metabolism improves age-related reproduction in C. elegans - Nature Metabolism

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Enhanced branched-chain amino acid metabolism improves age-related reproduction in C. elegans - Nature Metabolism

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