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Parkin inhibits proliferation and migration of bladder cancer via ubiquitinating Catalase - Communications Biology

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Parkin inhibits proliferation and migration of bladder cancer via ubiquitinating Catalase - Communications Biology

PRKN is a key gene involved in mitophagy in Parkinson's disease. However, recent studies have demonstrated that it also plays a role in the development and metastasis of several types of cancers, both in a mitophagy-dependent and mitophagy-independent manner. Despite this, the potential effects and underlying mechanisms of Parkin on bladder cancer (BLCA) remain unknown. Therefore, in this study, we investigated the expression of Parkin in various BLCA cohorts derived from human.

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Parkin inhibits proliferation and migration of bladder cancer via ubiquitinating Catalase - Communications Biology

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Parkin inhibits proliferation and migration of bladder cancer via ubiquitinating Catalase - Communications Biology

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