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A bispecific antibody approach for the potential prophylactic treatment of inherited bleeding disorders - Nature Cardiovascular Research
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Inherited bleeding disorders such as Glanzmann thrombasthenia (GT) lack prophylactic treatment options. As a result, serious bleeding episodes are treated acutely with blood product transfusions or frequent, repeated intravenous administration of recombinant activated coagulation factor VII (rFVIIa).
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