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COBRA improves the completeness and contiguity of viral genomes assembled from metagenomes - Nature Microbiology

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COBRA improves the completeness and contiguity of viral genomes assembled from metagenomes - Nature Microbiology

Viruses are often studied using metagenome-assembled sequences, but genome incompleteness hampers comprehensive and accurate analyses. Contig Overlap Based Re-Assembly (COBRA) resolves assembly breakpoints based on the de Bruijn graph and joins contigs. Here we benchmarked COBRA using ocean and soil viral datasets. COBRA accurately joined the assembled sequences and achieved notably higher genome accuracy than binning tools.

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COBRA improves the completeness and contiguity of viral genomes assembled from metagenomes - Nature Microbiology

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COBRA improves the completeness and contiguity of viral genomes assembled from metagenomes - Nature Microbiology

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