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Repurposing the dopamine transporter antagonist vanoxerine to treat colorectal cancer - Nature Cancer

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Repurposing the dopamine transporter antagonist vanoxerine to treat colorectal cancer - Nature Cancer

Self-renewing cancer stem cells drive tumor initiation and progression and represent a major target for therapeutic development. A study now shows that vanoxerine, a dopamine transporter antagonist, precisely inhibits this cell population in colorectal cancer, which leads to attenuation of tumor initiation and increased infiltration by immune cells.

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Repurposing the dopamine transporter antagonist vanoxerine to treat colorectal cancer - Nature Cancer

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Repurposing the dopamine transporter antagonist vanoxerine to treat colorectal cancer - Nature Cancer

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