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Distinct ontogenetic lineages dictate cDC2 heterogeneity - Nature Immunology
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Conventional dendritic cells (cDCs) include functionally and phenotypically diverse populations, such as cDC1s and cDC2s. The latter population has been variously subdivided into Notch-dependent cDC2s, KLF4-dependent cDC2s, T-bet+ cDC2As and T-bet− cDC2Bs, but it is unclear how all these subtypes are interrelated and to what degree they represent cell states or cell subsets.
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