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Motion of VAPB molecules reveals ER–mitochondria contact site subdomains - Nature

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Motion of VAPB molecules reveals ER–mitochondria contact site subdomains - Nature

To coordinate cellular physiology, eukaryotic cells rely on the rapid exchange of molecules at specialized organelle–organelle contact sites1,2. Endoplasmic reticulum–mitochondrial contact sites (ERMCSs) are particularly vital communication hubs, playing key roles in the exchange of signalling molecules, lipids and metabolites3,4. ERMCSs are maintained by interactions between complementary tethering molecules on the surface of each organelle5,6.

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Motion of VAPB molecules reveals ER–mitochondria contact site subdomains - Nature

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Motion of VAPB molecules reveals ER–mitochondria contact site subdomains - Nature

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