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Hagfish genome elucidates vertebrate whole-genome duplication events and their evolutionary consequences - Nature Ecology & Evolution
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Polyploidy or whole-genome duplication (WGD) is a major event that drastically reshapes genome architecture and is often assumed to be causally associated with organismal innovations and radiations. The 2R hypothesis suggests that two WGD events (1R and 2R) occurred during early vertebrate evolution.
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