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Pharmacological reactivation of p53 in the era of precision anticancer medicine - Nature Reviews Clinical Oncology

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Pharmacological reactivation of p53 in the era of precision anticancer medicine - Nature Reviews Clinical Oncology

p53, which is encoded by the most frequently mutated gene in cancer, TP53, is an attractive target for novel cancer therapies. Despite major challenges associated with this approach, several compounds that either augment the activity of wild-type p53 or restore all, or some, of the wild-type functions to p53 mutants are currently being explored.

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Pharmacological reactivation of p53 in the era of precision anticancer medicine - Nature Reviews Clinical Oncology

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Pharmacological reactivation of p53 in the era of precision anticancer medicine - Nature Reviews Clinical Oncology

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