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7 months ago

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Targeting PGLYRP1 promotes antitumor immunity while inhibiting autoimmune neuroinflammation - Nature Immunology

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Targeting PGLYRP1 promotes antitumor immunity while inhibiting autoimmune neuroinflammation - Nature Immunology

Co-inhibitory and checkpoint molecules suppress T cell function in the tumor microenvironment, thereby rendering T cells dysfunctional. Although immune checkpoint blockade is a successful treatment option for multiple human cancers, severe autoimmune-like adverse effects can limit its application.

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Targeting PGLYRP1 promotes antitumor immunity while inhibiting autoimmune neuroinflammation - Nature Immunology

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Targeting PGLYRP1 promotes antitumor immunity while inhibiting autoimmune neuroinflammation - Nature Immunology

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