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An extra-erythrocyte role of haemoglobin body in chondrocyte hypoxia adaption - Nature

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An extra-erythrocyte role of haemoglobin body in chondrocyte hypoxia adaption - Nature

Although haemoglobin is a known carrier of oxygen in erythrocytes that functions to transport oxygen over a long range, its physiological roles outside erythrocytes are largely elusive1,2. Here we found that chondrocytes produced massive amounts of haemoglobin to form eosin-positive bodies in their cytoplasm. The haemoglobin body (Hedy) is a membraneless condensate characterized by phase separation.

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An extra-erythrocyte role of haemoglobin body in chondrocyte hypoxia adaption - Nature

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An extra-erythrocyte role of haemoglobin body in chondrocyte hypoxia adaption - Nature

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