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Curved adhesions mediate cell attachment to soft matrix fibres in three dimensions - Nature Cell Biology

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Curved adhesions mediate cell attachment to soft matrix fibres in three dimensions - Nature Cell Biology

Integrin-mediated focal adhesions are the primary architectures that transmit forces between the extracellular matrix (ECM) and the actin cytoskeleton. Although focal adhesions are abundant on rigid and flat substrates that support high mechanical tensions, they are sparse in soft three-dimensional (3D) environments. Here we report curvature-dependent integrin-mediated adhesions called curved adhesions.

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environment ecology nature earth adhesions cell matrix soft fibres

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Curved adhesions mediate cell attachment to soft matrix fibres in three dimensions - Nature Cell Biology

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Curved adhesions mediate cell attachment to soft matrix fibres in three dimensions - Nature Cell Biology

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