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Cerebrospinal fluid-contacting neurons: multimodal cells with diverse roles in the CNS - Nature Reviews Neuroscience

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Cerebrospinal fluid-contacting neurons: multimodal cells with diverse roles in the CNS - Nature Reviews Neuroscience

The cerebrospinal fluid (CSF) is a complex solution that circulates around the CNS, and whose composition changes as a function of an animal's physiological state. Ciliated neurons that are bathed in the CSF — and thus referred to as CSF-contacting neurons (CSF-cNs) — are unusual polymodal interoceptive neurons. As chemoreceptors, CSF-cNs respond to variations in pH and osmolarity and to bacterial metabolites in the CSF.

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Cerebrospinal fluid-contacting neurons: multimodal cells with diverse roles in the CNS - Nature Reviews Neuroscience

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Cerebrospinal fluid-contacting neurons: multimodal cells with diverse roles in the CNS - Nature Reviews Neuroscience

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