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A fast chemical reprogramming system promotes cell identity transition through a diapause-like state - Nature Cell Biology

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A fast chemical reprogramming system promotes cell identity transition through a diapause-like state - Nature Cell Biology

Cellular reprogramming by only small molecules holds enormous potentials for regenerative medicine. However, chemical reprogramming remains a slow process and labour intensive, hindering its broad applications and the investigation of underlying molecular mechanisms. Here, through screening of over 21,000 conditions, we develop a fast chemical reprogramming (FCR) system, which significantly improves the kinetics of cell identity rewiring. We

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A fast chemical reprogramming system promotes cell identity transition through a diapause-like state - Nature Cell Biology

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A fast chemical reprogramming system promotes cell identity transition through a diapause-like state - Nature Cell Biology

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