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Cholesterol modulates the physiological response to nanoparticles by changing the composition of protein corona - Nature Nanotechnology

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Cholesterol modulates the physiological response to nanoparticles by changing the composition of protein corona - Nature Nanotechnology

Nanoparticles (NPs) in biological fluids form a layer of biomolecules known as the protein corona. The protein corona has been shown to determine the biological identity and in vivo fate of NPs, but whether and how metabolites, especially disease-related small molecules, regulate the protein corona and subsequently impact NP fate in vivo is relatively poorly understood. Here we report on the effects of cholesterol on the generation of protein corona and subsequent effects. We

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Cholesterol modulates the physiological response to nanoparticles by changing the composition of protein corona - Nature Nanotechnology

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Cholesterol modulates the physiological response to nanoparticles by changing the composition of protein corona - Nature Nanotechnology

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