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Immune evasion and ACE2 binding affinity contribute to SARS-CoV-2 evolution - Nature Ecology & Evolution

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Immune evasion and ACE2 binding affinity contribute to SARS-CoV-2 evolution - Nature Ecology & Evolution

Mutations in the SARS-CoV-2 genome could confer resistance to pre-existing antibodies and/or increased transmissibility. The recently emerged Omicron subvariants exhibit a strong tendency for immune evasion, suggesting adaptive evolution. However, because previous studies have been limited to specific lineages or subsets of mutations, the overall evolutionary trajectory of SARS-CoV-2 and the underlying driving forces are still not fully understood. Here we analysed all

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Immune evasion and ACE2 binding affinity contribute to SARS-CoV-2 evolution - Nature Ecology & Evolution

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Immune evasion and ACE2 binding affinity contribute to SARS-CoV-2 evolution - Nature Ecology & Evolution

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