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Nuclear class 3 PI3K coactivates circadian clock - Nature Cell Biology

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Nuclear class 3 PI3K coactivates circadian clock - Nature Cell Biology

Class 3 phosphatidylinositol-3-kinase (PI3K) has a surprising nuclear function as a coactivator of the circadian clock Bmal1–Clock transcription factor complex for rhythmic purine nucleotide metabolism. This finding opens new avenues for establishing the roles of nuclear subunits of class 3 PI3K in metabolic homeostasis.

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Nuclear class 3 PI3K coactivates circadian clock - Nature Cell Biology

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Nuclear class 3 PI3K coactivates circadian clock - Nature Cell Biology

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