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Antifibrotic therapy in nonalcoholic steatohepatitis: time for a human-centric approach - Nature Reviews Gastroenterology & Hepatology

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Antifibrotic therapy in nonalcoholic steatohepatitis: time for a human-centric approach - Nature Reviews Gastroenterology & Hepatology

Nonalcoholic steatohepatitis (NASH) might soon become the leading cause of end-stage liver disease and indication for liver transplantation worldwide. Fibrosis severity is the only histological predictor of liver-related morbidity and mortality in NASH identified to date. Moreover, fibrosis regression is associated with improved clinical outcomes. However, despite numerous clinical trials of plausible drug candidates, an approved antifibrotic therapy remains elusive.

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Antifibrotic therapy in nonalcoholic steatohepatitis: time for a human-centric approach - Nature Reviews Gastroenterology & Hepatology

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Antifibrotic therapy in nonalcoholic steatohepatitis: time for a human-centric approach - Nature Reviews Gastroenterology & Hepatology

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