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PI16+ reticular cells in human palatine tonsils govern T cell activity in distinct subepithelial niches - Nature Immunology
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Fibroblastic reticular cells (FRCs) direct the interaction and activation of immune cells in discrete microenvironments of lymphoid organs. Despite their important role in steering innate and adaptive immunity, the age- and inflammation-associated changes in the molecular identity and functional properties of human FRCs have remained largely unknown.
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