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A link between STK signalling and capsular polysaccharide synthesis in Streptococcus suis - Nature Communications

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A link between STK signalling and capsular polysaccharide synthesis in Streptococcus suis - Nature Communications

Synthesis of capsular polysaccharide (CPS), an important virulence factor of pathogenic bacteria, is modulated by the CpsBCD phosphoregulatory system in Streptococcus. Serine/threonine kinases (STKs, e.g. Stk1) can also regulate CPS synthesis, but the underlying mechanisms are unclear. Here, we identify a protein (CcpS) that is phosphorylated by Stk1 and modulates the activity of phosphatase CpsB in Streptococcus suis, thus linking Stk1 to CPS synthesis.

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A link between STK signalling and capsular polysaccharide synthesis in Streptococcus suis - Nature Communications

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A link between STK signalling and capsular polysaccharide synthesis in Streptococcus suis - Nature Communications

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