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Ornithine aminotransferase supports polyamine synthesis in pancreatic cancer - Nature

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Ornithine aminotransferase supports polyamine synthesis in pancreatic cancer - Nature

There is a need to develop effective therapies for pancreatic ductal adenocarcinoma (PDA), a highly lethal malignancy with increasing incidence1 and poor prognosis2. Although targeting tumour metabolism has been the focus of intense investigation for more than a decade, tumour metabolic plasticity and high risk of toxicity have limited this anticancer strategy3,4.

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Ornithine aminotransferase supports polyamine synthesis in pancreatic cancer - Nature

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Ornithine aminotransferase supports polyamine synthesis in pancreatic cancer - Nature

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