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Basal stem cell progeny establish their apical surface in a junctional niche during turnover of an adult barrier epithelium - Nature Cell Biology
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Barrier epithelial organs face the constant challenge of sealing the interior body from the external environment while simultaneously replacing the cells that contact this environment. New replacement cells—the progeny of basal stem cells—are born without barrier-forming structures such as a specialized apical membrane and occluding junctions. Here, we investigate how new progeny acquire barrier structures as they integrate into the intestinal epithelium of adult Drosophila. We
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