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1 year ago

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Targeting epigenetic regulators to overcome drug resistance in cancers - Signal Transduction and Targeted Therapy

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Targeting epigenetic regulators to overcome drug resistance in cancers - Signal Transduction and Targeted Therapy

Drug resistance is mainly responsible for cancer recurrence and poor prognosis. Epigenetic regulation is a heritable change in gene expressions independent of nucleotide sequence changes. As the common epigenetic regulation mechanisms, DNA methylation, histone modification, and non-coding RNA regulation have been well studied. Increasing evidence has shown that aberrant epigenetic regulations contribute to tumor resistance.

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Targeting epigenetic regulators to overcome drug resistance in cancers - Signal Transduction and Targeted Therapy

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Targeting epigenetic regulators to overcome drug resistance in cancers - Signal Transduction and Targeted Therapy

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Unlocking the Power of Knowledge
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