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The hTERT-p50 homodimer inhibits PLEKHA7 expression to promote gastric cancer invasion and metastasis - Oncogene

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The hTERT-p50 homodimer inhibits PLEKHA7 expression to promote gastric cancer invasion and metastasis - Oncogene

Although accumulating evidence has highlighted the molecular mechanisms by which hTERT promotes tumour cell invasion and metastasis, the molecular mechanisms of the properties enabling hTERT to contribute to invasion and metastasis have not been clearly illustrated. Here, we report that hTERT promotes gastric cancer invasion and metastasis by recruiting p50 to synergistically inhibit PLEKHA7 expression.

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The hTERT-p50 homodimer inhibits PLEKHA7 expression to promote gastric cancer invasion and metastasis - Oncogene

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The hTERT-p50 homodimer inhibits PLEKHA7 expression to promote gastric cancer invasion and metastasis - Oncogene

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Unlocking the Power of Knowledge
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