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1 year ago

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Exhausted T cells in tumors gain suppressor activity and can restrain immunity - Nature Immunology

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Exhausted T cells in tumors gain suppressor activity and can restrain immunity - Nature Immunology

Exhausted effector T cells accumulate in tumors and are the intended targets of cancer immunotherapy. New data suggest that upon infiltration and subsequent exhaustion in the tumor microenvironment, these T cells can take on an immunosuppressive function — and work against the immune response to cancer.

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Exhausted T cells in tumors gain suppressor activity and can restrain immunity - Nature Immunology

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Exhausted T cells in tumors gain suppressor activity and can restrain immunity - Nature Immunology

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