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Sensory nerve niche regulates mesenchymal stem cell homeostasis via FGF/mTOR/autophagy axis - Nature Communications

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Sensory nerve niche regulates mesenchymal stem cell homeostasis via FGF/mTOR/autophagy axis - Nature Communications

Mesenchymal stem cells (MSCs) reside in microenvironments, referred to as niches, which provide structural support and molecular signals. Sensory nerves are niche components in the homeostasis of tissues such as skin, bone marrow and hematopoietic system. However, how the sensory nerve affects the behavior of MSCs remains largely unknown. Here we show that the sensory nerve is vital for mesenchymal tissue homeostasis and maintenance of MSCs in the continuously growing adult mouse incisor.

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Sensory nerve niche regulates mesenchymal stem cell homeostasis via FGF/mTOR/autophagy axis - Nature Communications

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Sensory nerve niche regulates mesenchymal stem cell homeostasis via FGF/mTOR/autophagy axis - Nature Communications

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