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The antitumour effects of caloric restriction are mediated by the gut microbiome - Nature Metabolism

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The antitumour effects of caloric restriction are mediated by the gut microbiome - Nature Metabolism

Calorie restriction (CR) and intermittent fasting (IF) without malnutrition reduce the risk of cancer development. Separately, CR and IF can also lead to gut microbiota remodelling. However, whether the gut microbiota has a role in the antitumour effect related to CR or IF is still unknown. Here we show that CR, but not IF, protects against subcutaneous MC38 tumour formation through a mechanism that is dependent on the gut microbiota in female mice.

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The antitumour effects of caloric restriction are mediated by the gut microbiome - Nature Metabolism

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The antitumour effects of caloric restriction are mediated by the gut microbiome - Nature Metabolism

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