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Targeting T cell checkpoints and myeloid suppressor cells is effective in pancreatic cancer - Nature Cancer

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Targeting T cell checkpoints and myeloid suppressor cells is effective in pancreatic cancer - Nature Cancer

Modulation of T cell immune checkpoints combined with inhibition of chemokine receptors on myeloid-derived suppressor cells can reprogram the highly suppressive tumor immune microenvironment of pancreatic ductal adenocarcinoma (PDAC), and generates durable complete responses in a PDAC mouse model. These results provide a testable clinical regimen for human PDAC.

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Targeting T cell checkpoints and myeloid suppressor cells is effective in pancreatic cancer - Nature Cancer

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Targeting T cell checkpoints and myeloid suppressor cells is effective in pancreatic cancer - Nature Cancer

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