Article
LAP1 supports nuclear adaptability during constrained melanoma cell migration and invasion - Nature Cell Biology
Rating:
0.0
Views:
66
Likes:
1
Library:
1
Metastasis involves dissemination of cancer cells away from a primary tumour and colonization at distal sites. During this process, the mechanical properties of the nucleus must be tuned since they pose a challenge to the negotiation of physical constraints imposed by the microenvironment and tissue structure. We discovered increased expression of the inner nuclear membrane protein LAP1 in metastatic melanoma cells, at the invasive front of human primary melanoma tumours and in metastases.
Rating:
0.0
Views:
66
Likes:
1
Library:
1
Rate This Post
Rate The Educational Value
Rate The Ease of Understanding and Presentation
Interesting or Boring? Rate the Entertainment Value