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An inflammatory state remodels the immune microenvironment and improves risk stratification in acute myeloid leukemia - Nature Cancer
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Acute myeloid leukemia (AML) is a hematopoietic malignancy with poor prognosis and limited treatment options. Here we provide a comprehensive census of the bone marrow immune microenvironment in adult and pediatric patients with AML. We characterize unique inflammation signatures in a subset of AML patients, associated with inferior outcomes.
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