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Matrix viscoelasticity controls spatiotemporal tissue organization - Nature Materials

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Matrix viscoelasticity controls spatiotemporal tissue organization - Nature Materials

Biomolecular and physical cues of the extracellular matrix environment regulate collective cell dynamics and tissue patterning. Nonetheless, how the viscoelastic properties of the matrix regulate collective cell spatial and temporal organization is not fully understood. Here we show that the passive viscoelastic properties of the matrix encapsulating a spheroidal tissue of breast epithelial cells guide tissue proliferation in space and in time.

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Matrix viscoelasticity controls spatiotemporal tissue organization - Nature Materials

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Matrix viscoelasticity controls spatiotemporal tissue organization - Nature Materials

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