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Integration of single-cell transcriptomes and biological function reveals distinct behavioral patterns in bone marrow endothelium - Nature Communications

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Integration of single-cell transcriptomes and biological function reveals distinct behavioral patterns in bone marrow endothelium - Nature Communications

Heterogeneity of endothelial cell (EC) populations reflects their diverse functions in maintaining tissue's homeostasis. However, their phenotypic, molecular, and functional properties are not entirely mapped. We use the Tie2-CreERT2;Rosa26-tdTomato reporter mouse to trace, profile, and cultivate primary ECs from different organs. As paradigm platform, we use this strategy to study bone marrow endothelial cells (BMECs).

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Integration of single-cell transcriptomes and biological function reveals distinct behavioral patterns in bone marrow endothelium - Nature Communications

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Integration of single-cell transcriptomes and biological function reveals distinct behavioral patterns in bone marrow endothelium - Nature Communications

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