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Lasso-grafted designer cytokines - Nature Biomedical Engineering

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Lasso-grafted designer cytokines - Nature Biomedical Engineering

Cytokine receptor agonists can be designed with longer half-lives in circulation and with enhanced penetration of the blood–brain barrier by genetically grafting macrocyclic peptides into the structural loops of fragment crystallizable regions.

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Lasso-grafted designer cytokines - Nature Biomedical Engineering

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Lasso-grafted designer cytokines - Nature Biomedical Engineering

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