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Programmable self-regulated molecular buffers for precise sustained drug delivery - Nature Communications

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Programmable self-regulated molecular buffers for precise sustained drug delivery - Nature Communications

Unlike artificial nanosystems, biological systems are ideally engineered to respond to their environment. As such, natural molecular buffers ensure precise and quantitative delivery of specific molecules through self-regulated mechanisms based on Le Chatelier's principle. Here, we apply this principle to design self-regulated nucleic acid molecular buffers for the chemotherapeutic drug doxorubicin and the antimalarial agent quinine.

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Programmable self-regulated molecular buffers for precise sustained drug delivery - Nature Communications

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Programmable self-regulated molecular buffers for precise sustained drug delivery - Nature Communications

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