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A modern automated patch-clamp approach for high throughput electrophysiology recordings in native cardiomyocytes - Communications Biology
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Crucial conventional patch-clamp approaches to investigate cellular electrophysiology suffer from low-throughput and require considerable experimenter expertise. Automated patch-clamp (APC) approaches are more experimenter independent and offer high-throughput, but by design are predominantly limited to assays containing small, homogenous cells.
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