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Chimeric antigen receptor T cell therapy for autoimmune disease - Nature Reviews Immunology

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Chimeric antigen receptor T cell therapy for autoimmune disease - Nature Reviews Immunology

Infusion of T cells engineered to express chimeric antigen receptors (CARs) that target B cells has proven to be a successful treatment for B cell malignancies. This success inspired the development of CAR T cells to selectively deplete or modulate the aberrant immune responses that underlie autoimmune disease. Promising results are emerging from clinical trials of CAR T cells targeting the B cell protein CD19 in patients with B cell-driven autoimmune diseases.

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Chimeric antigen receptor T cell therapy for autoimmune disease - Nature Reviews Immunology

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Chimeric antigen receptor T cell therapy for autoimmune disease - Nature Reviews Immunology

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