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Mitochondrial transfer mediates endothelial cell engraftment through mitophagy - Nature

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Mitochondrial transfer mediates endothelial cell engraftment through mitophagy - Nature

Ischaemic diseases such as critical limb ischaemia and myocardial infarction affect millions of people worldwide1. Transplanting endothelial cells (ECs) is a promising therapy in vascular medicine, but engrafting ECs typically necessitates co-transplanting perivascular supporting cells such as mesenchymal stromal cells (MSCs), which makes clinical implementation complicated2,3. The mechanisms that enable MSCs to facilitate EC engraftment remain elusive.

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Mitochondrial transfer mediates endothelial cell engraftment through mitophagy - Nature

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Mitochondrial transfer mediates endothelial cell engraftment through mitophagy - Nature

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