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26 days ago

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Synthetic dual co-stimulation increases the potency of HIT and TCR-targeted cell therapies - Nature Cancer

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Synthetic dual co-stimulation increases the potency of HIT and TCR-targeted cell therapies - Nature Cancer

Chimeric antigen receptor T cells have dramatically improved the treatment of hematologic malignancies. T cell antigen receptor (TCR)-based cell therapies are yet to achieve comparable outcomes. Importantly, chimeric antigen receptors not only target selected antigens but also reprogram T cell functions through the co-stimulatory pathways that they engage upon antigen recognition.

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Synthetic dual co-stimulation increases the potency of HIT and TCR-targeted cell therapies - Nature Cancer

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Synthetic dual co-stimulation increases the potency of HIT and TCR-targeted cell therapies - Nature Cancer

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