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High production of IL-12 by human dendritic cells stimulated with combinations of pattern-recognition receptor agonists - npj Vaccines

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High production of IL-12 by human dendritic cells stimulated with combinations of pattern-recognition receptor agonists - npj Vaccines

The cytokine IL-12p70 is crucial for T helper 1 (Th1) polarization and the generation of type 1 immunity required to fight cancer and pathogens. Therefore, strategies to optimize the production of IL-12p70 by human dendritic cells (DCs) may significantly improve the efficacy of vaccines and immunotherapies. However, the rules governing the production of IL-12p70 remain obscure.

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High production of IL-12 by human dendritic cells stimulated with combinations of pattern-recognition receptor agonists - npj Vaccines

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High production of IL-12 by human dendritic cells stimulated with combinations of pattern-recognition receptor agonists - npj Vaccines

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