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11 days ago

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Illuminating cortactin structure and function at actin filament branches - Nature Structural & Molecular Biology

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Illuminating cortactin structure and function at actin filament branches - Nature Structural & Molecular Biology

Stabilization of a branch structure would intuitively suggest a direct connection between trunk and bough, but in actin filament networks, cortactin clamps the branching Arp2/3 complex to the daughter filament. This has fundamental consequences for mechanistic understanding of actin branch turnover and cortactin biology.

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Illuminating cortactin structure and function at actin filament branches - Nature Structural & Molecular Biology

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Illuminating cortactin structure and function at actin filament branches - Nature Structural & Molecular Biology

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