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19 days ago

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Periportal macrophages protect against commensal-driven liver inflammation - Nature

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Periportal macrophages protect against commensal-driven liver inflammation - Nature

The liver is the main gateway from the gut, and the unidirectional sinusoidal flow from portal to central veins constitutes heterogenous zones, including the periportal vein (PV) and the pericentral vein zones1–5. However, functional differences in the immune system in each zone remain poorly understood. Here intravital imaging revealed that inflammatory responses are suppressed in PV zones.

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Periportal macrophages protect against commensal-driven liver inflammation - Nature

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Periportal macrophages protect against commensal-driven liver inflammation - Nature

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