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Viral remodeling of the 4D nucleome - Experimental & Molecular Medicine

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Viral remodeling of the 4D nucleome - Experimental & Molecular Medicine

The dynamic spatial organization of genomes across time, referred to as the four-dimensional nucleome (4DN), is a key component of gene regulation and biological fate. Viral infections can lead to a reconfiguration of viral and host genomes, impacting gene expression, replication, latency, and oncogenic transformation. This review provides a summary of recent research employing three-dimensional genomic methods such as Hi–C, 4C, ChIA-PET, and HiChIP in virology.

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Viral remodeling of the 4D nucleome - Experimental & Molecular Medicine

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Viral remodeling of the 4D nucleome - Experimental & Molecular Medicine

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