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Structural insights into double-stranded RNA recognition and transport by SID-1 - Nature Structural & Molecular Biology

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Structural insights into double-stranded RNA recognition and transport by SID-1 - Nature Structural & Molecular Biology

RNA uptake by cells is critical for RNA-mediated gene interference (RNAi) and RNA-based therapeutics. In Caenorhabditis elegans, RNAi is systemic as a result of SID-1-mediated double-stranded RNA (dsRNA) across cells. Despite the functional importance, the underlying mechanisms of dsRNA internalization by SID-1 remain elusive.

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Structural insights into double-stranded RNA recognition and transport by SID-1 - Nature Structural & Molecular Biology

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Structural insights into double-stranded RNA recognition and transport by SID-1 - Nature Structural & Molecular Biology

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